Serum plasminogen activator urokinase receptor predicts elevated risk of acute respiratory distress syndrome in patients with sepsis and is positively associated with disease severity, inflammation and mortality.

Serum plasminogen activator urokinase receptor predicts elevated risk of acute respiratory distress syndrome in patients with sepsis and is positively associated with disease severity, inflammation and mortality.

This study aims to evaluate the predictive value of serum plasinnase activator receptors dissolved in with ARDS. As many as 57 patients with ARDS and 58 sepsis patients without ARD were recruited for current case-control studies. Laboratory tests, acute physiology and chronic health evaluation (Apache) scores and scores of serial organ failure assessment (sofas) are evaluated, and mortality during hospitalization are recorded. Blood samples were collected and serum flares were detected by Elisa. Furthermore, the necrosis factor of tumor (TNF) -α, interleukin (IL) -1β, IL-6, IL-8, IL-10 and IL-17, and C-reactive (CRP) protein is detected.

The results showed that serum levels of shame in sepsis patients with ARD were higher than in patients with sepsis without ARDS. Character analysis Receiver (ROC) The curve showed that it was possible to distinguish sepsis patients with ARDS from sepsis patients without ARDS based on their serum supar levels, and multivariate logistic regression analysis showed that serum supar levels were independent predictors of the risk of Ards in sepsis patients. In patient sepsis with ARDS, Super Serum levels are positively correlated with Apache II scores, sofa scores and CRP, TNF-α, IL-1β and IL-8 levels. In addition, super super levels are lower on survivors compared to those who are not congratulations, and the analysis of the ROC curve shows that Serum Simpar is able to predict the probability of mortality.

In conclusion, serum flares independently estimate the increased risk of ARD in patients with sepsis, and correlated / related to the severity of greater disease, higher inflammation and increased mortality in patients with sepsis and ards.

Urokinase placentogenic activator: potential thrombolytic agent for ischemic stroke.

Stroke continues to be one of the main causes of mortality and morbidity throughout the world. The restoration of cerebral blood flow with recombinant plasminogen activator (RTPA) with or without mechanical trombectomy is considered as the most effective therapy to save brain tissue from ischemic damage, but this requires highly skilled and professional facilities, with a high cost of the Plasminogen Activator urokinase context (UPA) Generally used as an alternative.

This literature review summarizes existing studies related to the potential for upa clinical applications in ischemic stroke patients. In the translation study of ischemic stroke, the UPA has been proven to promote nerve regeneration and reduce the volume of infarction and neurological deficits. Clinical trials employ upa as thrombolytic agents have replicated this favorable results and reported a consistent increase in the recanization, functional increase and the level of brain bleeding, similar to observed with RTPA. Zymogen Pro-urokinase (pro-UPA) and RTPA seems to be complementary and synergistic in their actions, indicating that their administration can increase the efficacy of thrombolysis without affecting the risk of bleeding as a whole. Large clinical trials that examine the efficacy of the upa or a combination of pro-UPAs and RTPA are highly required to reveal whether the therapeutic approach can be the choice of first-line care that is safe for patients with ischemic strokes.

Given the limited data that exists, thrombolysis with an upa seems to be a potential alternative for repercative treatment that is mediated by RTPA because of its beneficial effects on revascularization promotions and nerve regeneration.

 Serum plasminogen activator urokinase receptor predicts elevated risk of acute respiratory distress syndrome in patients with sepsis and is positively associated with disease severity, inflammation and mortality.
Serum plasminogen activator urokinase receptor predicts elevated risk of acute respiratory distress syndrome in patients with sepsis and is positively associated with disease severity, inflammation and mortality.

Diagnostic and Prognostic values ​​of Plasminogen activator receptors Dissolved urokinase type (Supar) in glomerosclerosis and the impact of segmental focal detection methods.

The plasminogen type of urokinase plasma type receptor (Supar) is a biomarker for segmental focal glomerosclerosis (FSGS), but the value is being discussed because ambiguous results arise from various ELISA methods in previous research. The purpose of this study was to compare the diagnostic performance of the two leading voice Elisa kits and examine four objectives in 146 subjects: (1) Super plasma levels in accordance with glomerular disease (Primary FSG, secondary and repeated after kidney transplantation, other glomerulonephritis) and in that control healthy; (2) Super level based on the glomerulus filtration rate; (3) the sensitivity and specificity of the flare for the diagnosis of the FSGS and the optimal determination of cut-off; (4) Supar as a prognostic tool. Patients with FSG show super higher super values ​​than patients with other glomerulonephritis and healthy individuals. This is applied to the subject with and without chronic kidney disease.

Although Suparnostic ™ test and Kuantikine Human Elisa Kit Elisa provides high sensitivity and specificity for the diagnosis of FSGS, their cut-off value of 4.644 ng / ml and 2,789 ng / ml differ significantly. Super higher the next prediction for the development of the final stages of kidney disease. In short, the flare value must be interpreted in the population context and the testing method used. Knowing a specific cut-off test makes a valuable biomarker sound for FSGs. Retino acid is one of the most famous agents that can induce differentiation on several types of tumors. Unfortunately, most biased tumors for differentiation cues.

Urokinase,

4793-1000 each
EUR 1618.8

Urokinase

E8ET1703-26 100ul
EUR 275
Description: Available in various conjugation types.

Urokinase

enz-264 100µg
EUR 145
Description: Human Urokinase

Urokinase

enz-965 1µg
EUR 60
Description: Recombinant Human Urokinase

Urokinase

MBS8534429-01mL 0.1mL
EUR 345

Urokinase

MBS8534429-01mLAF405L 0.1mL(AF405L)
EUR 565

Urokinase

MBS8534429-01mLAF405S 0.1mL(AF405S)
EUR 565

Urokinase

MBS8534429-01mLAF610 0.1mL(AF610)
EUR 565

Urokinase

MBS8534429-01mLAF635 0.1mL(AF635)
EUR 565

Urokinase

THP-0021 1 vial
EUR 3198.4
Description: Protein

OPPA00786-100UG - Urokinase Human - Human Urokinase Protein

OPPA00786-100UG 100ug
EUR 154

Human Urokinase

21560039-1 100 µg
EUR 154.66

Human Urokinase

7-03802 100µg Ask for price

Human Urokinase

7-03803 1mg Ask for price

Human Urokinase

7-03804 5mg Ask for price

Human Urokinase

RP-1463 100 ug
EUR 196.8

Urokinase Human

rAP-1334 Inquiry Ask for price

Human Urokinase

MBS142405-01mg 0.1mg
EUR 310

Human Urokinase

MBS142405-1mg 1mg
EUR 485

Human Urokinase

MBS142405-5mg 5mg
EUR 1260

Human Urokinase

MBS142405-5x5mg 5x5mg
EUR 5345

Urokinase protein

30C-CP8107 50 ug
EUR 347
Description: Purified Recombinant Human Urokinase protein

Urokinase protein

MBS537132-005mg 0.05mg
EUR 510

Urokinase protein

MBS537132-5x005mg 5x0.05mg
EUR 2065

Urokinase antibody

5793-100 each
EUR 405.6

Urokinase antibody

5793-30T each
EUR 175.2

Urokinase Antibody

abx024172-200ul 200 ul
EUR 693.6

Urokinase Antibody

49439 100ul
EUR 499

Urokinase Antibody

49439-100ul 100ul
EUR 399.6

Urokinase Antibody

49439-50ul 50ul
EUR 286.8

Urokinase Antibody

F51093-0.4ML 0.4 ml
EUR 322.15
Description: PLAU, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders. PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin. The protein is found in high and low molecular mass forms. Each consists of two chains, A and B. The high molecular mass form contains a long chain A. Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain. The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis. Structurally, PLAU contains 1 EGF-like domain and 1 kringle domain.

Urokinase Antibody

F52084-0.4ML 0.4 ml
EUR 322.15
Description: Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.

Urokinase Antibody

GWB-444707 0.25 mg Ask for price

Urokinase Antibody

GWB-24B3D4 1 mg Ask for price

Urokinase Receptor

MBS601813-005mg 0.05mg
EUR 645

Urokinase Receptor

MBS601813-025mg 0.25mg
EUR 875

Urokinase Receptor

MBS601813-5x025mg 5x0.25mg
EUR 3785

Urokinase Antibody

MBS9436184-005mL 0.05mL
EUR 325

Urokinase Antibody

MBS9436184-01mL 0.1mL
EUR 435

Urokinase Antibody

MBS9436184-5x01mL 5x0.1mL
EUR 1810

Urokinase, Human (LMW)

MBS654001-01mg 0.1mg
EUR 995

Urokinase, Human (LMW)

MBS654001-5x01mg 5x0.1mg
EUR 4250

Urokinase, Human (HMW)

MBS653988-01mg 0.1mg
EUR 800

Urokinase, Human (HMW)

MBS653988-5x01mg 5x0.1mg
EUR 3370

Human LMW urokinase

MBS135608-01mg 0.1mg
EUR 540

Human LMW urokinase

MBS135608-1mg 1mg
EUR 3440

Human LMW urokinase

MBS135608-5x1mg 5x1mg
EUR 15240

Human HMW Urokinase

MBS135613-01mg 0.1mg
EUR 450

Human HMW Urokinase

MBS135613-1mg 1mg
EUR 2945

Human HMW Urokinase

MBS135613-5x1mg 5x1mg
EUR 13010

Human Urokinase (HMW)

MBS480672-01mg 0.1mg
EUR 515

Human Urokinase (HMW)

MBS480672-5x01mg 5x0.1mg
EUR 2100

Human Urokinase (LMW)

MBS480676-01mg 0.1mg
EUR 625

Human Urokinase (LMW)

MBS480676-5x01mg 5x0.1mg
EUR 2595

Mouse Urokinase (LMW)

MBS480781-005mg 0.05mg
EUR 850

Mouse Urokinase (LMW)

MBS480781-5x005mg 5x0.05mg
EUR 3615

Urokinase Rabbit mAb

59337 100ul
EUR 339

Urokinase Rabbit pAb

E2381717 100ul
EUR 225
Description: Available in various conjugation types.

Urokinase Rabbit pAb

MBS8543181-01mL 0.1mL
EUR 305

Urokinase Rabbit pAb

MBS8543181-01mLAF405L 0.1mL(AF405L)
EUR 565

Urokinase Rabbit pAb

MBS8543181-01mLAF405S 0.1mL(AF405S)
EUR 565

Urokinase Rabbit pAb

MBS8543181-01mLAF610 0.1mL(AF610)
EUR 565

Urokinase Rabbit pAb

MBS8543181-01mLAF635 0.1mL(AF635)
EUR 565

Active Dog Urokinase

MBS135639-005mg 0.05mg
EUR 475

Active Dog Urokinase

MBS135639-01mg 0.1mg
EUR 720

Active Dog Urokinase

MBS135639-5x01mg 5x0.1mg
EUR 3000

Urokinase, Human Urine

MBS653743-01mg 0.1mg
EUR 470

Urokinase, Human Urine

MBS653743-1mg 1mg
EUR 795

Urokinase, Human Urine

MBS653743-5x1mg 5x1mg
EUR 3430

Rabbit anti Urokinase

MBS315817-1mg 1mg
EUR 1135

Rabbit anti Urokinase

MBS315817-5x1mg 5x1mg
EUR 4925

Urokinase, Human urine

HY-108904 5 mg
EUR 541.13
Description: Urokinase (peptidolytic) (EC 3.4.21.73) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research[1].

Active Rabbit Urokinase

MBS135609-005mg 0.05mg
EUR 595

Active Rabbit Urokinase

MBS135609-01mg 0.1mg
EUR 1500

Active Rabbit Urokinase

MBS135609-5x01mg 5x0.1mg
EUR 6505

Mouse Urokinase Antibody

GWB-E77CED 0.2 mg Ask for price

Mouse Urokinase Antibody

GWB-F17B9C 1 mg Ask for price

Mouse Urokinase Antibody

GWB-D66B4D 1 mg Ask for price

Active Porcine Urokinase

MBS135982-005mg 0.05mg
EUR 485

Active Porcine Urokinase

MBS135982-01mg 0.1mg
EUR 780

Active Porcine Urokinase

MBS135982-5x01mg 5x0.1mg
EUR 3280

Urokinase Sepharose Beads

7927-1 each
EUR 261.6

Urokinase Sepharose Beads

7927-25 each
EUR 2114.4

Urokinase Sepharose Beads

7927-5 each
EUR 836.4

Rat Urokinase ELISA kit

E01A17267 96T
EUR 700
Description: ELISA

Rat Urokinase ELISA kit

E02U0010-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Urokinase ELISA kit

E02U0010-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Urokinase ELISA kit

E02U0010-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Urokinase ELISA kit

E08U0010-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Urokinase ELISA kit

E08U0010-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Urokinase ELISA kit

E08U0010-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Urokinase ELISA kit

E07U0010-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Urokinase ELISA kit

E07U0010-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Urokinase ELISA kit

E07U0010-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Cat Urokinase ELISA Kit

MBS063492-INQUIRE INQUIRE Ask for price

Rat Urokinase ELISA Kit

MBS034751-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Urokinase ELISA Kit

MBS034751-48StripWells 48-Strip-Wells
EUR 550

Rat Urokinase ELISA Kit

MBS034751-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Urokinase ELISA Kit

MBS034751-96StripWells 96-Strip-Wells
EUR 765

Rat Urokinase ELISA Kit

NSL0062r 96 Tests
EUR 498

Rat Urokinase ELISA Kit

MBS727186-10x96StripWells 10x96-Strip-Wells
EUR 5685

Rat Urokinase ELISA Kit

MBS727186-48StripWells 48-Strip-Wells
EUR 485

Rat Urokinase ELISA Kit

MBS727186-5x96StripWells 5x96-Strip-Wells
EUR 3020

Rat Urokinase ELISA Kit

MBS727186-96StripWells 96-Strip-Wells
EUR 690

Human Urokinase (LMW) HRP

MBS480677-01mg 0.1mg
EUR 790

Human Urokinase (LMW) HRP

MBS480677-5x01mg 5x0.1mg
EUR 3315

Rat Urokinase ELISA Kit

MBS264941-10x96StripWells 10x96-Strip-Wells
EUR 3290

Rat Urokinase ELISA Kit

MBS264941-48StripWells 48-Strip-Wells
EUR 295

Rat Urokinase ELISA Kit

MBS264941-5x96StripWells 5x96-Strip-Wells
EUR 1800

Rat Urokinase ELISA Kit

MBS264941-96StripWells 96-Strip-Wells
EUR 450

Rat Urokinase ELISA Kit

EIA06502r each
EUR 480

Urokinase protein (Low MW)

30C-CP4014 3 KU
EUR 43
Description: Purified native Human Urokinase protein (Low MW)

Goat Urokinase ELISA kit

E01A52163 96T
EUR 700
Description: ELISA

Goat Urokinase ELISA kit

E06U0010-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Urokinase ELISA kit

E06U0010-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Urokinase ELISA kit

E06U0010-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Urokinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Duck Urokinase ELISA Kit

MBS090506-INQUIRE INQUIRE Ask for price

Fish Urokinase ELISA Kit

MBS015225-INQUIRE INQUIRE Ask for price

Goat Urokinase ELISA Kit

MBS039924-INQUIRE INQUIRE Ask for price

Cavy Urokinase ELISA Kit

MBS041254-INQUIRE INQUIRE Ask for price

Urokinase Mixed Human 95%

GWB-37FE97 10000 Unit Ask for price

Goat Urokinase ELISA Kit

NSL0033Gt 96T
EUR 528

Goat Urokinase ELISA Kit

MBS745082-10x96StripWells 10x96-Strip-Wells
EUR 5685

Goat Urokinase ELISA Kit

MBS745082-48StripWells 48-Strip-Wells
EUR 485

Goat Urokinase ELISA Kit

MBS745082-5x96StripWells 5x96-Strip-Wells
EUR 3020

Goat Urokinase ELISA Kit

MBS745082-96StripWells 96-Strip-Wells
EUR 690

Active Rat Urokinase, HMW

MBS135623-005mg 0.05mg
EUR 480

Active Rat Urokinase, HMW

MBS135623-01mg 0.1mg
EUR 775

Active Rat Urokinase, HMW

MBS135623-5x01mg 5x0.1mg
EUR 3265

Human Urokinase (LMW) FITC

MBS480678-01mg 0.1mg
EUR 790

Human Urokinase (LMW) FITC

MBS480678-5x01mg 5x0.1mg
EUR 3315

Active Rat Urokinase, HMW

MBS480800-005mg 0.05mg
EUR 535

Active Rat Urokinase, HMW

MBS480800-5x005mg 5x0.05mg
EUR 2175

Urokinase protein (Low MW)

MBS537950-3000Units 3000Units
EUR 150

Urokinase protein (Low MW)

MBS537950-5x3000Units 5x3000Units
EUR 520

Goat Urokinase ELISA Kit

MBS262216-10x96StripWells 10x96-Strip-Wells
EUR 3545

Goat Urokinase ELISA Kit

MBS262216-48StripWells 48-Strip-Wells
EUR 310

Goat Urokinase ELISA Kit

MBS262216-5x96StripWells 5x96-Strip-Wells
EUR 1940

Goat Urokinase ELISA Kit

MBS262216-96StripWells 96-Strip-Wells
EUR 475

Goat Urokinase ELISA Kit

EIA06502Go each
EUR 520

Urokinase, human recombinant

7696-10 each
EUR 261.6

Urokinase, human recombinant

7696-50 each
EUR 652.8

Urokinase, human recombinant

7696-500 each
EUR 2271.6

Urokinase Human Recombinant

rAP-1424 Inquiry Ask for price

Recombinant Human Urokinase

MBS147135-0001mg 0.001mg
EUR 240

Recombinant Human Urokinase

MBS147135-0005mg 0.005mg
EUR 310

Recombinant Human Urokinase

MBS147135-005mg 0.05mg
EUR 1360

Recombinant Human Urokinase

MBS147135-5x005mg 5x0.05mg
EUR 5800

Immobilized human urokinase

MBS135763-1mL 1mL
EUR 845

Immobilized human urokinase

MBS135763-5x1mL 5x1mL
EUR 3565

Inactivated Mouse Urokinase

MBS136020-005mg 0.05mg
EUR 880

Inactivated Mouse Urokinase

MBS136020-01mg 0.1mg
EUR 1380

Inactivated Mouse Urokinase

MBS136020-5x01mg 5x0.1mg
EUR 5985

Immobilized human urokinase

MBS480749-1mL 1mL
EUR 940

The purpose of this investigation is to analyze the impact of prolonged treatment with retinoat acid on two cell lines from the nerve bias to differentiation. Cells are also treated with retinate acid in combination with polymerase poly (ADP-Ribos) polymerase inhibitors (PARP) because PARP1 is a chromatin modulator that is known and can affect the process of differentiation.

Dustin

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Comparative study on the efficacy and safety of alteplase and urokinase in the treatment of acute cerebral infarction

Independent impact of periodontitis and cardiovascular disease on elevated soluble urokinase-type plasminogen activator receptor levels

Independent impact of periodontitis and cardiovascular disease on elevated soluble urokinase-type plasminogen activator receptor levels

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